The Hidden Dangers of Over-the-Counter Pain Medications for Pets
- Stephanye Quinn
- Sep 10, 2025
- 2 min read
When our pets are in pain, it’s natural to want to help them feel better as quickly as possible. Many pet parents reach for the same medications they use for themselves, such as ibuprofen (Advil®), acetaminophen (Tylenol®), or naproxen (Aleve®). While this instinct comes from a place of love, giving over-the-counter (OTC) pain medications designed for humans can be extremely dangerous—and sometimes even fatal—for dogs and cats.

Why Human Pain Medications Are Unsafe for Dogs
Dogs process medications very differently than people. Even small doses of certain OTC pain relievers can cause severe illness. Common risks include:
Ibuprofen & Naproxen (Advil®, Motrin®, Aleve®): These NSAIDs can cause stomach ulcers, intestinal bleeding, kidney failure, and neurological issues.
Acetaminophen (Tylenol®): Just one or two tablets can damage a dog’s liver and affect red blood cells, leading to life-threatening complications.
Aspirin: While sometimes used in specific veterinary cases, aspirin is not considered a safe long-term solution and can still cause ulcers, bleeding, and kidney problems.
Because dogs are more sensitive to these drugs, there is no safe “human dose” that can be given without veterinary guidance.
Signs of Toxicity to Watch For
If a dog accidentally ingests human pain medication, symptoms can appear quickly. Call your veterinarian immediately if you notice:
Vomiting, diarrhea, or black/tarry stools
Loss of appetite or lethargy
Pale gums or weakness
Increased thirst or urination
Jaundice (yellowing of gums, eyes, or skin)
Tremors, seizures, or unsteadiness
Safe Alternatives for Pain Relief
There are safe, effective pain medications for dogs—but they must be prescribed by a veterinarian. Depending on your pet’s condition, your vet may recommend veterinary-approved NSAIDs, joint supplements, physical therapy, or other supportive treatments.
What to Do if Your Dog is in Pain
If your dog seems uncomfortable, resist the urge to medicate at home. Instead:
Call your veterinarian and describe the symptoms.
Schedule an exam to determine the underlying cause of the pain.
Follow your vet’s recommendations for safe pain management.
Human pain medications should never be given to dogs without veterinary approval. Even a single pill can have serious consequences. The best way to help your pet feel better is to work with your veterinary team to find safe and effective treatment options.



